Journal ยท Berat Badan dan Metabolisme

When Weight Loss Medication Is Not Worth It

Medication is not the first step if sleep, thyroid, insulin resistance or resistance training have not been addressed. The real cost also includes the maintenance phase.

Updated 7 October 2026  ·  Reviewed by Dr Munirah Hishamshah · MMC 62691

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Quick Answer

Medication is not the first step if sleep, thyroid, insulin resistance or resistance training have not been addressed. The real cost also includes the maintenance phase.

There is one sentence we hear often enough that it deserves an open answer. It runs roughly like this: I do not think this weight loss medication is working for me, the weight has barely moved, it feels like money wasted. The answer is not reassurance. Sometimes it is true, and medication is not worth it for that case.

When we say do not start

There are several situations where we do not recommend drug therapy as a first step, even when the patient arrives intending to begin.

  • Sleep has never been addressed, and there are signs of sleep apnoea that have not been investigated
  • Thyroid function has never been tested
  • Insulin resistance has never been measured, so there is no baseline to compare against later
  • No resistance training at all in the routine, so part of the weight lost will come from muscle
  • The target loss is small enough to reach without medication in a reasonable time

In cases like these there is very likely another step that returns more for less cost. Telling someone to start on medication while they sleep four hours a night is not treatment, it is selling.

Why some people feel the medication is not working

Three reasons come up most. First, expectations were set by social media rather than by data, so a normal result feels disappointing. Second, the medication was given with no nutrition or training plan, so it works alone and delivers half of what it could. Third, there is a barrier that was never checked, and medication does not fix a barrier. Read the barriers that get overlooked.

The real cost is not the monthly cost

Many people work out the cost of treatment as the monthly price multiplied by the number of months. That is incomplete. The real cost includes consultation, baseline testing, periodic monitoring, and the maintenance phase after medication stops. The part most often left out of the sum is maintenance. People budget only for the months on medication, then stop outright, the weight returns, and the cycle starts again at full price. A plan that includes maintenance from the start is usually cheaper across two years.

When it genuinely is worth it

Drug therapy makes more sense when there is a metabolic condition to manage rather than simply a number on the scale. Prediabetes, confirmed insulin resistance, high blood pressure, uncontrolled lipids, or weight related sleep apnoea. In those situations treatment targets health risk rather than appearance, and the return is measured on blood tests rather than in the mirror alone.

What you should get before you pay

Before anything starts, you should receive a breakdown that names the consultation, the tests, the monitoring, the review schedule and the maintenance plan. There should be a clear review date, and if that date arrives with no measurable change, the plan gets changed rather than simply continued. Any plan that cannot give you that breakdown deserves a question.

Next step

If you are not sure whether this treatment is reasonable for your case, an assessment is the right step, not a purchase. Book a consultation, or read why medication is not the easy way out.

The health-risk background for body weight sits in the WHO fact sheet.

Every iLIV guide is written and reviewed under our editorial standards, and each one carries the name of the reviewing doctor together with their MMC registration number.

Frequently Asked

When is weight loss medication not the first step?

When sleep has not been addressed, thyroid has not been tested, insulin resistance has not been measured, or there is no resistance training at all in the routine.

Why do some people feel the medication is not working?

Three common reasons: expectations set by social media, medication given with no nutrition or training plan, or a barrier that was never checked.

What should the cost breakdown include?

Consultation, baseline tests, periodic monitoring, a review schedule and a maintenance plan. If the review date arrives with no measurable change, the plan gets changed.

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